The contents of the respule should be gently squeezed into the nebulizer cup. ketoconazole, itraconazole HIV protease inhibitors and cobicistat-containing products, can therefore increase systemic exposure to budesonide. Monitor the growth of pediatric patients receiving budesonide respules routinely (e.g., via stadiometry). Infants in the placebo arm experienced an average growth of 3.7 cm over 12 weeks compared with 3.5 cm and 3.1 cm in the Budesonide respules 0.5 mg and 1 mg arms respectively. In glucocorticoid receptor affinity studies, the 22R form was two times as active as the 22S epimer. This is not likely to be relevant for humans given recommended doses, but therapy with inhaled budesonide should be regularly reviewed and maintained at the lowest effective dose. In animal studies, glucocorticosteroids have been shown to induce malformations. Dosage schedules: The dose delivered to the patient varies depending on the nebulizing equipment used. Advising the patient to rinse the mouth out with water after each dosing will minimise the risk. As with other drugs administered during pregnancy, the benefit of the administration of budesonide for the mother should be weighed against the risks to the foetus. Clinical trials with 13119 patients on inhaled budesonide and 7278 patients on placebo have been pooled. Solve your problem quick & easy with online consultation. This corresponds to estimated mean (95% CI) reductions in 12-week growth velocity between placebo and Budesonide respules 0.5 mg of 0.2 cm (-0.6 to 1.0) and between placebo and Budesonide respules 1 mg of 0.6 cm (-0.2 to 1.4). Budesonide is a white to off-white, tasteless, odorless powder that is practically insoluble in water and in heptane, sparingly soluble in ethanol, and freely soluble in chloroform.Please enter the Unique ID (UID) given by Cipla Representative. BUDECORT 0.5 mg Respules Each 2 ml contains Budesonide IP ...... 0.5 mg BUDECORT 1 mg Respules Each 2 ml contains Budesonide IP...... 1 mg However, on an individual basis, 7 patients in this study (6 in the Budesonide respules treatment arms and 1 in the placebo arm) experienced a shift from having a normal baseline stimulated cortisol level to having a subnormal level at Week 12. You should not increase or decrease your dose without seeking medical advice. All the risks and benefits should be discussed with the doctor before using this medicine. Budesonide is provided as a mixture of two epimers (22R and 22S). All the risks and benefits should be discussed with the doctor before using this medicine.This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.This medicine should be used with caution in patients with osteoporosis since this medicine may cause loss of bone density and further worsen the existing condition. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.Patients using this medicine for extended periods of time should be examined for candida infection or any other signs of adverse effects on the nasal and oral mucosa. Budecort 0.5 MG Respules is used for the maintenance treatment of asthma in patients aged three months and above. The dose should be titrated to the minimum effective dose to reduce the chances of such side effects. 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