We comply with the HONcode standard for trustworthy health information - Discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.If you experience symptoms such as sharp pain and swelling in the leg, difficulty breathing, chest pain, blurred vision, or difficulty speaking, contact your doctor immediately.If you experience signs of decreased liver function, such as nausea, vomiting, diarrhea, loss of appetite, weight loss, yellowing of the skin or whites of the eyes, dark urine, or pale stools, contact your doctor as soon as possible.There may be an interaction between danazol and any of the following:All material copyright MediResource Inc. 1996 – 2020. She had a large heterogeneous hepatic tumor, a well-differentiated hepatocellullar carcinoma in a non-cirrhotic liver.The hypothesis that hepatocellular carcinoma had been caused by danazol was accepted in the absence of other causes [It has been stressed in a recent and very extensive American review that the benefit to harm balance of androgen replacement has still not been adequately examined [In this connection it may also be noted that, following a joint meeting in 2004, the International Society of Andrology, the International Society for the Study of the Aging Male, and the European Association of Urology revised their earlier recommendations on the definition, diagnosis, and management of late onset hypogonadism [A particular reason for caution is the fact that in this age group there will be a fair proportion of subjects at risk of prostate cancer. Voltaren is a nonsteroidal anti-inflammatory drug (NSAID).Diclofenac works by reducing substances in the body that cause pain and inflammation. doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: If no response or an incomplete response is obtained, the dose may be increased to 200 mg twice daily. In the treatment of endometriosis, danazol affects hormone levels resulting in changes in the endometrial tissue (that usually lines the uterus but exists outside of the uterus in endometriosis) so that these tissues become inactive and decrease in size.In the treatment of fibrocystic breast disease, danazol results in the relief of pain and tenderness and decreases breast nodules. The following side effects have been reported by at least 1% of people taking this medication. advice about side effects. Many of these side effects can be managed, and some may go away on their own over time.If you have a history of clotting, you may be at increased risk of experiencing blood-clot-related problems such as heart attack, stroke, or clots in the deep veins of your leg. This prevents prostaglandin synthesis (prostaglandins elevate body temperature and make nerve endings more sensitive to … Other drugs may interact with danazol, including prescription and over-the-counter medicines, Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use danazol only for the indication prescribed.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.Copyright 1996-2020 Cerner Multum, Inc. Danazol, USP is a synthetic steroid derived from ethisterone. Tell your doctor about any such situation that affects you. The drug has an adverse effect on the lipoprotein profile, resulting in a decrease of high-density lipoproteins (HDLs) and an increase of low-density lipoproteins, and may be associated with increased liver enzymes. Danazol, sold as Danocrine and other brand names, is a medication used in the treatment of endometriosis, fibrocystic breast disease, hereditary angioedema and other conditions. taken, how much, and when it happened. Tell any doctor who treats you that you are using this medicine.Women who take danazol to treat endometriosis should start the medication during a menstrual period.Danazol is usually given for 3 to 9 months to treat endometriosis. However, many people have no side effects or only have minor side effects. The effectiveness of therapy is directly related to induction of amenorrhea. 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